Rejuran Polynucleotide Skin Booster Treatment in London

The durability of results following a Rejuran booster course depends on individual skin condition, age, lifestyle, and the number of sessions completed. In most cases, the improvements in texture, elasticity, and overall skin quality developed through a full course persist for six to twelve months. Maintenance sessions every four to six months are commonly recommended to sustain the regenerative benefits over time. Your practitioner will confirm a realistic outlook during your initial clinical assessment based on your specific concerns and treatment plan.

Rejuran contains highly purified polynucleotide fragments that have been processed to remove immunogenic proteins, reducing the risk of adverse immune responses. Because the treatment uses no live cellular material or synthetic volumising agents, it is generally regarded as suitable for selected patients when used following appropriate clinical assessment. As with any injectable procedure, individual medical history and clinical suitability must be carefully evaluated before treatment begins. Suitability is confirmed during a thorough face-to-face consultation prior to any treatment being carried out at this clinic.

Rejuran treatment may cause temporary side effects such as redness, swelling, bruising, small bumps, and mild tenderness at the injection sites. In rare cases, patients may experience allergic reactions, infection, prolonged swelling, or uneven skin texture, particularly if the procedure is performed incorrectly or proper aftercare is not followed.

The appropriate number of sessions depends on individual skin concerns, the degree of existing damage or ageing, and the goals established during consultation. Most patients begin with a course of three sessions, spaced three to four weeks apart, to allow cumulative treatment response to develop progressively across the dermis. Patients with milder concerns or those already in a maintenance phase may respond well to fewer sessions. A personalised treatment plan confirming session frequency and spacing is provided following your clinical assessment.

A topical anaesthetic cream is applied in advance, which significantly reduces discomfort during the injection process. The nappage technique used to distribute polynucleotides across the treatment zone may produce a mild, brief stinging sensation at individual injection sites. Most patients describe the experience as tolerable, and any discomfort typically resolves promptly once the session is complete. Where sensitivity is a concern, your practitioner will adjust the approach to support comfort throughout.

Rejuran treatment is associated with minimal downtime in most cases. A common, transient response includes small papules at the injection sites, alongside mild redness or slight swelling, which typically subside within 24 to 48 hours. These responses reflect normal tissue activity in the early phase of the repair process. Detailed aftercare guidance is provided at the end of each session. Most patients are able to resume their usual daily activities the same day or the following morning.

Rejuran skin booster treatment may be appropriate for adults with fine lines, uneven texture, dull or dehydrated skin, post-inflammatory hyperpigmentation, acne scarring, or progressive loss of skin quality associated with ageing or photodamage. It is generally suitable across a range of skin types and tones. Individuals who are pregnant or breastfeeding, or those with certain underlying health conditions, may not be appropriate candidates. Suitability is determined through a clinical assessment during your initial consultation.

Initial improvements in hydration and surface luminosity may be noticeable within the first two to three weeks after treatment, as early tissue response begins to develop. Greater improvements in skin texture, firmness, and visible fine line reduction may develop more progressively over four to eight weeks as ongoing tissue remodelling continues beneath the surface.

Rejuran skin booster injections are frequently combined with microneedling to improve dermal penetration of polynucleotides and support overall treatment response through a dual-action mechanism. The treatment may also be integrated with other rejuvenation protocols — such as energy-based treatments or complementary skin booster formulations — depending on individual clinical assessment. Some clinicians combine Rejuran and Profhilo to address both structural regeneration and deep hydration within the same overall plan. Sequencing and timing of any combined approach are planned carefully during consultation.